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8 Evaluation of Men Jump to section + Causes of male infertility include infection, injury, toxin exposures, anatomic variances, chromosomal abnormalities, systemic diseases, and sperm antibodies. The sperm must provide the zygote with DNA, centrioles, and activation factor for the embryo to develop. Vasectomy. (PDF, 5 MB) From the Encyclopedia of Reproduction, 1999. A variety of disorders ranging from hormonal disturbances to physical problems, to psychological problems can cause male infertility.  Although many treatment options are now available, in many cases treatment will not work.  In many instances, male infertility is caused by testicular damage resulting in an inability of the testicle to produce sperm.  Once damaged, the testicle will not usually regain its sperm-making capabilities; this aspect of male infertility is analogous to menopause (though not natural like menopause) for women and cannot usually be treated.  Despite medicine�s limited ability to treat male infertility, many successful treatment options are available for its many causes.  Besides testicular damage, the main causes of male infertility are low sperm production and poor sperm quality.   The Causes of Male Infertility Male infertility has many causes--from hormonal imbalances, to physical problems, to psychological and/or behavioral problems.  Moreover, fertility reflects a man�s �overall� health.  Men who live a healthy lifestyle are more likely to produce healthy sperm.  The following list highlights some lifestyle choices that negatively impact male fertility--it is not all-inclusive: · Smoking--significantly decreases both sperm count and sperm cell motility. · Prolonged use of marijuana and other recreational drugs. · Chronic alcohol abuse. · Anabolic steroid use--causes testicular shrinkage and infertility. · Overly intense exercise--produces high levels of adrenal steroid hormones which cause a    testosterone deficiency resulting in infertility. · Inadequate vitamin C and Zinc in the diet. · Tight underwear--increases scrotal temperature which results in decreased sperm production. · Exposure to environmental hazards and toxins such as pesticides, lead, paint, radiation, radioactive   substances, mercury,  benzene, boron, and heavy metals · Malnutrition and anemia. · Excessive stress! 6-Mb Deletion of the Human Y Chromosome Persists Through Balance Between Recurrent Mutation and Haploid Selection. (PDF, 295 KB) Nature Genetics, 2003. The main side effects are hot flushes, gastrointestinal events (nausea and vomiting), headache, back pain, and leg cramps.

Symptoms include: bloating constipation dark urine diarrhea nausea abdominal pain vomiting They are usually mild and easy to treat. If the egg does not travel, it can be harder to conceive naturally. Treatment[edit] Treatment depends on the cause of infertility, but may include counselling, fertility treatments, which include in vitro fertilization. Ovulation disorders About one quarter of infertility cases are due to ovulation disorders. After ruling out female infertility concerns, tests for male infertility may be needed.

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Insurance for Infertility in India

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Debate over whether health insurance companies (e.g. in the US) should be required to cover infertility treatment. Infertility in women was ranked the 5th highest serious global disability5&6 (among populations under the age of 60).

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National Collaborating Centre for Women's and Children's Health. Oligospermia is the most frequent cause of male infertility. The Use of Epididymal Sperm in Assisted Reproduction. (PDF, 8 MB) Chapter from textbook, Frontiers in Endocrinology: Perspectives on Assisted Reproduction, 1994. Common causes of infertility of females include: ovulation problems (e.g. polycystic ovarian syndrome, PCOS, the leading reason why women present to fertility clinics due to anovulatory infertility.[58]) tubal blockage pelvic inflammatory disease caused by infections like tuberculosis age-related factors uterine problems previous tubal ligation endometriosis advanced maternal age immune infertility Males[edit] The main cause of male infertility is low semen quality. Kidney Transplantation in Inbred Rats. (PDF, 6 MB) The American Journal of Surgery, 1973.

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Causes in women Infertility in women can also have a range of causes. Vasectomy. (PDF, 5 MB) From the Encyclopedia of Reproduction, 1999. Being obese or overweight: This can increase the risk of infertility in women as well as men. The patient must be treated with bromocriptine (eg, Parlodel) at an initial dose of 2. Irregular periods The average woman’s cycle is 28 days long. Programming of Ovarian Stimulation with Norethindrone Acetate in IVF/GIFT Cycles. (PDF, 2 MB) Human Reproduction, 1989.


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