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Less than 50% motility may significantly affect the ability for sperm to fertilize the egg without therapy; and (4) morphology, or shape – there are three parts of the sperm that are analyzed for morphology: the head, midpeice, and tail. In vitro fertilization[edit] IVF is the most commonly used ART.

Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. Sperm are then collected, washed, and added to the eggs in the dish. Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility.

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This abnormality is usually surgically corrected in infancy. Steroids used to build muscles can shrink the testes and may lead to decreased sperm production. Effects[edit] Psychological[edit] The consequences of infertility are manifold and can include societal repercussions and personal suffering. The treating doctor may feel inadequacy and the trust between the doctor and patient breaks down [43]. Testicular neoplasia, commonly producing estrogen, usually causes infertility. By 2014, over 5 million people had been born after being conceived through IVF.

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IVF treatment may be suggested if IUI is not successful or appropriate, or if female infertility is a contributing problem. In-vitro fertilization and donor insemination are major procedures involved. Out of this group, the following statistics on the cause of infertility generally apply: One-third of couples will discover fertility problems in only the man.

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Debate over whether health insurance companies (e.g. in the US) should be required to cover infertility treatment. This technique is called hand-assist laparoscopy. Bromocriptine is used in cases when anovulation is caused by an elevated level of the hormone prolactin. Women in group III can conceive only with oocyte donation and in vitro fertilization.