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Paternal age > or = 40 years: an important risk factor for infertility. 8 If a woman has irregular cycles, the testing should be conducted later in the cycle, starting seven days before presumed onset of menses, and repeated weekly until menses. Blood test: This can assess hormone levels and whether a woman is ovulating.

Normal cervical mucus to allow passage of the sperm to the upper genital tract. Chlamydia test: Chlamydia can affect fertility, but antibiotics can treat it. Several days later, embryos -- or fertilized eggs -- get put back into your uterus with a device called an intrauterine insemination catheter. A defect in any of these sperm structures may result in infertility that will not be detected by semen analysis.[60] Antisperm antibodies cause immune infertility.[23][24] Cystic fibrosis can lead to infertility in men. Aetiology of Congenital Absence of Vas Deferens: Genetic Study of Three Generations. (PDF, 4 MB) Human Reproduction, 1993. Simultaneous Treatment of the Wife in Infertile Couples with Oligospermia. (PDF, 4 MB) Fertility and Sterility, 1983.

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Sperm retrieval for azoospermia and intracytoplasmic sperm injection success rates – A personal overview. (PDF, 1 MB) Human Fertility, 2010. They compete with endogenous GnRH molecules for the pituitary receptors and provoke a massive release of gonadotropins into circulation.

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2012;27(8):2396–2404.   Want to use this article elsewhere? Exposure to some chemicals: Some pesticides, herbicides, metals, such as lead, and solvents have been linked to fertility problems in both men and women. Techniques for the Resolution of Testicular Obstruction. (PDF, 8 MB) Chapter 78 from textbook, Reconstructive Urology, 1992. In-vitro fertilization and donor insemination are major procedures involved.

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Nonfunctional pituitary tumors may compress the pituitary stalk or the gonadotropic cells, interrupting the proper chain of signals leading to pituitary failure. If you’ve been diagnosed with infertility, or fear you may have trouble conceiving in the future, you’re not alone. Ovulation induction agents increase the risk of multiple pregnancy, ovarian hyperstimulation syndrome, and thrombosis, and they may increase the risk of ovarian cancer in women who remain nulliparous. Intrauterine insemination (IUI): At the time of ovulation, a fine catheter is inserted through the cervix into the uterus to place a sperm sample directly into the uterus. The presence of open tubes is essential for natural conception, as sperm must traverse the tubes in order to reach and fertilize the ovulated egg. Men who are underweight tend to have lower sperm concentrations than those who are at a normal BMI. Patients with severe ovarian hyperstimulation syndrome are often hospitalized and confined to bed, with strict control of fluid intake and output. First-line therapy is the ultrasound-guided transvaginal puncture. Patients may be candidates for assisted reproduction techniques after appropriate genetic screening in the partner.[29] Acquired blockage of the ductal system Genital ducts may become obstructed secondary to infections, such as chlamydia, gonorrhea, tuberculosis, and smallpox. A sperm count of under 15 million is considered low.