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For a woman to conceive, certain things have to happen: vaginal intercourse must take place around the time when an egg is released from her ovary; the system that produces eggs has to be working at optimum levels; and her hormones must be balanced.[54] For women, problems with fertilisation arise mainly from either structural problems in the Fallopian tube or uterus or problems releasing eggs. Other medical techniques are e.g. tuboplasty, assisted hatching, and preimplantation genetic diagnosis. 6,8 It is important for primary care physicians to be familiar with the workup and prognosis for infertile couples. The risk of ovarian hyperstimulation syndrome and multiple pregnancy is heightened; therefore, hMG should be started at the minimal dose (75 IU SC qd for 7 days).

When a man ejaculates and releases semen through the penis, the seminal fluid, or semen, helps transport the sperm toward the egg. Ovulation induction in polycystic ovary syndrome [published corrections appear in J Obstet Gynaecol Can. It was broken down into male and female categories.

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2012;27(8):2396–2404.   Want to use this article elsewhere? Factors Affecting Fertility (Continued) Among other factors affecting the probability of conception are: Age of women. The likelihood of fertilization improves significantly for men with low sperm concentrations. It can also help if a man has severe erectile dysfunction.

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Sperm count often returns to normal after stopping the medication. Congenital Absence of the Vas Deferens: The Fertilizing Capacity of Human Epididymal Sperm. (PDF, 3 MB) New England Journal of Medicine, 1990. Vause TD, Cheung AP, Sierra S, et al.; Society of Obstetricians and Gynecologists of Canada. Earn up to 6 CME credits per issue.     To see the full article, log in or purchase access.

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Women with anovulation may be treated in the primary care setting with clomiphene to induce ovulation. Fertility is not an issue for some patients affected by DES, and they remain undiagnosed until they have an abnormal Papanicolaou test result. Infertility caused by DNA defects on the Y chromosome is passed on from father to son. The opening improves the ability of the embryo to implant into the uterine lining. Prader-Willi syndrome is caused by a disorder of genomic imprinting with deletions of paternally derived chromosome arm 15q11-13. When clomiphene binds to estrogen receptors in the hypothalamus, it leads to an increase release of an important signaling hormone called GnRH (gonadotropin releasing hormone). Segmental dysplasia is defined as a vas deferens with at least 2 distinct sites of vasal obstruction. Men should undergo evaluation with a semen analysis. Sterilisation Some women choose to be sterilised if they don't want to have any more children.