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London, United Kingdom: National Institute for Health and Clinical Excellence (NICE); February 2013:1–63. (Clinical guideline no. Alternatively, the patient may bypass surgical treatment and proceed directly to intrauterine insemination or in vitro fertilization, depending on the severity and the female partner's age. The more fetuses there are, the higher the risk of premature labor. For example, polycystic ovarian syndrome is when the eggs only partially developed within the ovary and there is an excess of male hormones. Ongoing Pregnancies and Birth after Intracytoplasmic Sperm Injection with Frozen-thawed Epididymal Spermatozoa. (PDF, 442 KB) Human Reproduction, 1995.

Factors contributing to the formation of antisperm antibodies in women are disturbance of normal immunoregulatory mechanisms, infection, violation of the integrity of the mucous membranes, rape and unprotected oral or anal sex. A Modern Approach to Male Infertility. (PDF, 2 MB) Serono Symposia, Insights Into Infertility Newsletter, 1997. Prevalence of Premature Ovarian Failure in Monozygotic and Dizygotic Twins. (PDF, 90 KB) Human Reproduction, 2007.

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The doctor may ask about the couple's sexual habits and make recommendations regarding these. Conception and Fertility The chance of conceiving in any given menstrual cycle is less than 20% in a woman of reproductive age. Adding recombinant human FSH to HCG has been shown to be effective in achieving spermatogenesis in most patients.[18] Select patients with adult-onset idiopathic hypogonadotropic hypogonadism may respond to clomiphene citrate therapy.[19] Prader-Willi syndrome Patients have characteristic obesity, mental retardation, small hands and feet, and hypogonadotropic hypogonadism due to a GnRH deficiency. She will also undergo a gynecologic examination and a number of tests: Laparoscopy involves inserting a thin tube with a camera on to investigate and possibly remove unwanted tissue. These rates, of course, readjusted down for the older women with long durations of infertility [42].

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Ovulation disorders About one quarter of infertility cases are due to ovulation disorders. Polyps and submucous fibroids can be removed during this procedure. 8  A normal sample according to the 2010 World Health Organization (WHO) guidelines is described in Table 2. Sperm counts can fluctuate, so that several samples may be necessary. Sexually transmitted infections (STIs): Chlamydia can damage the fallopian tubes in a woman and cause inflammation in a man's scrotum.

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In men who have the necessary reproductive organs to procreate, infertility can be caused by low sperm count due to endocrine problems, drugs, radiation, or infection. Semen analysis The semen analysis is a very important test and should be done early in the evaluation process. Most of infertile couples are aware of what can be offered to them from the media. Chemotherapy: Some types may significantly reduce sperm count. An ultrasound scan can detect an ectopic pregnancy. For this reason, it is less likely to adversely affect the endometrium and cervical mucus. Ross says it might suggest a blockage in the “plumbing” that can be corrected with surgery. Overheated testicles: Causes include an undescended testicle, a varicocele, or varicose vein in the scrotum, the use of saunas or hot tubs, wearing tight clothes, and working in hot environments. Epidemiology of Sterility and Infertility Sterility and infertility affect about 10 – 15% of couples.