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Clomiphene citrate for unexplained subfertility in women. Thyroid problems: An overactive or underactive thyroid gland can lead to a hormonal imbalance.

A detailed history and physical examination is necessary for both partners. Egg donation. This can help you if you have ovaries that don't work right but you have a normal uterus. Bhaskar Dutta/Photoshare Clinical definitions Infertility is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.”… (WHO-ICMART glossary1). “Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year. Patients who are suffering from Stein-Leventhal syndrome (also referred to as polycystic ovary syndrome, or PCOS) can also suffer from anovulation.[3] Up to 90% of cases of anovulation are caused by PCOS; this syndrome is usually hereditary.[4][5] Weight loss or anorexia can also cause hormonal imbalance, leading to irregular ovulation (dysovulation). The main symptom of infertility is not getting pregnant. A small ejaculate volume may be observed in patients with retrograde ejaculation, absence of the vas deferens or seminal vesicles, ductal obstruction, hypogonadotropism, or poor sympathetic response.

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Treatment[edit] Treatment depends on the cause of infertility, but may include counselling, fertility treatments, which include in vitro fertilization. Choose a single article, issue, or full-access subscription. Male infertility is defined as a male’s inability to cause a pregnancy after having regular intercourse (sex) with a fertile female without birth control for one year. 41 Treatment of Unexplained Infertility Jump to section + Couples who have no identified cause of infertility should be counseled on timing of intercourse for the most fertile period (i.e., the six days preceding ovulation).

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Heavy, long, or painful periods Heavy periods may indicate an underlying condition affecting fertility. Pregnancies after Testicular Sperm Extraction and Intracytoplasmic Sperm Injection in Non-obstructive Azoospermia. (PDF, 3 MB) Human Reproduction, 1995. Graft-versus-host Reactivity and Renal Allograft Survival in Rats Given Allogeneic Spleen Cells or Spleen Allografts.(PDF, 2 MB) Transplantation, 1976.

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Other hormones including inhibin B and leptin, may also be affected by obesity. Illegal drugs: Consumption of marijuana and cocaine can lower the sperm count. Fertilizing Capacity of Epididymal and Testicular Sperm with ICSI. (PDF, 5 MB) Frontiers in Endocrinology, 1995. Problems with ejaculation or ejaculate Having difficulty ejaculating or noticing changes in the ejaculate, such as a drop in volume, may also be a sign of an underlying issue related to a man's fertility. Placenta Percreta Invading Bladder. (PDF, 2 MB) The Journal of Urology, 1973. Epididymal Surgery. (PDF, 8 MB) Chapter 8 from textbook, Infertility, 1992. ART techniques generally start with stimulating the ovaries to increase egg production.