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If a cause for your fertility problems hasn't been identified, talk to your doctor about the next steps. A subgroup of patients has PCOS with hyperinsulinism, hyperandrogenism associated with acanthosis nigricans, and resistance to CC. [205, 206] This group is amenable to metformin treatment. [207, 208] Metformin improves insulin sensitivity and decreases hepatic gluconeogenesis and, therefore, reduces hyperinsulinism, basal and stimulated LH levels, and free testosterone concentration.

If a woman needs an HCG injection to activate ovulation and ultrasound scans show that too many follicles have developed, it is possible to withhold the HCG injection. Choice of infertility treatment often related to issues of efficacy, cost, ease of use or administration, and its side effects.

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Infertility and Endometriosis

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Most couples (approximately 85%) will achieve pregnancy within one year of trying, with the greatest likelihood of conception occurring during the earlier months. Cervical surgery can sometimes cause scarring or shortening of the cervix.

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Damaged Sperm Ducts: Seven percent of infertile men cannot transport sperm from their testicles to out of their penis.  This pathway may be blocked by a number of conditions: · A genetic or developmental mistake may block or cause the absence of one or both tubes (which   transport the sperm from the testes to the penis). · Scarring from tuberculosis or some STDs may block the epididymis or tubes. · An elective or accidental vasectomy may interrupt tube continuity. Varicocele and male factor infertility treatment: a new meta-analysis and review of the role of varicocele repair. Testicular Sperm Extraction (TESE) and Intracytoplasmic Sperm Injection (ICSI) for Non-obstructive Azoospermia.(PDF, 1 MB) 10th World Congress on In Vitro Fertilization and Assisted Reproduction, 1997.

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The quality of the cervical mucus can be improved with the administration of a small dose of estrogens, or the problem can be bypassed by intrauterine insemination. [163, 209] If the follicle is smaller than 23-24 mm at the time of ovulation, a better size can be obtained by starting the CC therapy on the menstrual cycle day 2. A couple should see a healthcare provider if they have not been able to become pregnant after 12 months of having sex regularly without birth control. Minimal Ovarian Stimulation (mini-IVF) for IVF Utilizing Vitrification and Cryopreserved Embryo Transfer. (PDF, 406 KB) Reproductive BioMedicine Online, 2010. Reversal of Vasectomy and the Treatment of Male Infertility. (PDF, 4 MB) Journal of Andrology, 1980. Most couples (about 84%) who have regular sexual intercourse (that is, every two to three days) and who do not use contraception get pregnant within a year. If the egg does not travel, it can be harder to conceive naturally. Antisperm antibodies may form when the blood-testis barrier is breached because of infection, vasectomy, testicular torsion, cryptorchidism, or testicular trauma.


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See also
Incidence of Infertility in India
Female Infertility and Pcos
Infertility Treatment in South Africa