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1) Advancing maternal age: Historically before the latter 20th century, women were conceiving in their teens and twenties, when age-related abnormalities with the egg were not evident. Undescended testicles During fetal development one or both testicles may fail to descend from the abdomen into the sac that normally contains the testicles.

It has been suggested that infertility be classified as a form of disability.[22] Causes[edit] Immune infertility[edit] Antisperm antibodies (ASA) have been considered as infertility cause in around 10–30% of infertile couples.[23] In both men and women, ASA production are directed against surface antigens on sperm, which can interfere with sperm motility and transport through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and impaired growth and development of the embryo. Further reading[edit] Fertility: Assessment and Treatment for People with Fertility Problems. Radiation therapy: If this is aimed near the reproductive organs, it can increase the risk of fertility problems. The surgeon can remove implants and scar tissue, and this may reduce pain and aid fertility. Hypothyroidism: Low thyroid hormone levels--can cause poor semen quality, poor testicular function and may disturb libido.  May be caused by a diet high in iodine.  Reducing iodine intake or beginning thyroid hormone replacement therapy can elevate sperm count.  This condition is found in only 1 percent of infertile men. 4) Uterine fibroids: Fibroids are very common (approximately 40% of women may have them) and the mere presence alone does not necessarily cause infertility.

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While chromosomal failure is usually caused by abnormalities of the sex chromosomes, autosomal disorders are also observed. 37,38 The addition of 1,500 to 1,700 mg of metformin (Glucophage) daily may increase ovulation and pregnancy rates, but it does not significantly improve live birth rates over clomiphene alone.

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Its treatment depends on the etiologic factor, but, in many instances, the underlying cause remains unknown. You take gonadotropins that trigger the development of more than one egg. Treatment of the cause: 23. Ovulation disorders: The WHO classifies ovulation disorders into 3 groups: 1. The following problems are possible: Low sperm count: The man ejaculates a low number of sperm. Metformin (Glucophage): If Clomifene is not effective, metformin may help women with PCOS, especially when linked to insulin resistance.

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Anabolic steroids: Popular with bodybuilders and athletes, long-term use can seriously reduce sperm count and mobility. 6,8,23 A high FSH level (10 to 20 mIU per mL [10 to 20 IU per L]) drawn on day 3 of the menstrual cycle is associated with infertility. Quantitative Evaluation of Spermatogenesis by Testicular Histology in Men with Congenital Absence of the Vas Deferens Undergoing Epididymal Sperm Aspiration. (PDF, 3 MB) Human Reproduction, 1990. Some personal habits are considered risk factors for infertility, such as excess alcohol intake [11] and cigarette smoking [12].