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Sertoli cells are columnar, with irregular basal nuclei that have prominent nucleoli and fine chromatin. Three main events necessary for pregnancy to occur are: Ovulation: the process by which the mature egg is released from one of the woman’s ovaries. Because of the action at the estrogen-receptor level within the hypothalamus, CC alleviates the negative feedback effect exerted by endogenous estrogens. [161, 162, 163] As a result, CC normalizes the GnRH release; therefore, the secretion of FSH and LH is capable of normalized follicular recruitment, selection, and development to reestablish the normal process of ovulation. [161, 164] The standard dose of CC is 50 mg PO qd for 5 days, starting on the menstrual cycle day 3-5 or after progestin-induced bleeding.

Results of one study investigating a cohort of 315 men revealed changes within the hinge region of SF-1 and no rare allelic variants in fertile control men. 6 Women with risk factors for tubal obstruction, such as endometriosis, previous pelvic infections, or ectopic pregnancy, should instead be offered hysteroscopy or laparoscopy with dye to assess for other pelvic pathology. A complete pelvic exam should reveal any uterine hypoplasia, fibroids, adnexal tumors or cervical lesions and should indicate whether dyspareunia may be a problem. Tubal catheterisation or cannulation: - With proximal tubal obstruction, selective salpingography plus tubal catheterisation, or hysteroscopic tubal cannulation, may be treatment options.

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Understanding what defines normal fertility is crucial to helping a person, or couple, know when it is time to seek help. Metformin (Glucophage) is another type of medication that may help you ovulate normally if you have insulin resistance or PCOS (polycystic ovarian syndrome). Its use is controversial in patients with a history of breast cancer. Other factors that can affect a woman's chances of conceiving include being overweight or underweight,[56] or her age as female fertility declines after the age of 30.[57] Sometimes it can be a combination of factors, and sometimes a clear cause is never established. However, the presence of fibroids alone doesn’t necessarily cause infertility or predispose a woman to pregnancy loss.

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Source : Infertility and its Treatments - PPT Presentation Summary : Infertility and Its Treatments. But if you haven’t had a period in months, it’s time to get your fertility checked.

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The testicular-epididymal component includes sperm and comprises about 5% of the ejaculate volume. Endometriosis can be treated with hormones that suppress the displaced endometrial tissue or the tissue can be removed by a surgical procedure. Practice Committee of American Society for Reproductive Medicine. This technique involves an injection of a single healthy sperm directly injected into mature egg. It has been proven useful in overcoming infertility conditions, such as blocked or damaged tubes, endometriosis, repeated IUI failure, unexplained infertility, poor ovarian reserve, poor or even nil sperm count. Electric or vibratory stimulation to achieve ejaculation: Ejaculation is achieved with electric or vibratory stimulation. In men who have the necessary reproductive organs to procreate, infertility can be caused by low sperm count due to endocrine problems, drugs, radiation, or infection. If necessary, they refer patients to a fertility clinic or local hospital for more specialized tests.