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Ovulation disorders About one quarter of infertility cases are due to ovulation disorders. Drugs used for both women and men[67] include clomiphene citrate, human menopausal gonadotropin (hMG), follicle-stimulating hormone (FSH), human chorionic gonadotropin (hCG), gonadotropin-releasing hormone (GnRH) analogues, aromatase inhibitors, and metformin. The initial dosage of clomiphene is 50 mg daily for five days starting on day 3 to 5 of the menstrual cycle. The testes are at risk for both thermal and physical trauma because of their exposed position. To ascertain a more precise assessment, a hysteroscopy of the uterus is run.

The ovulation induction agents used include clomiphene citrate, hMG, hCG, recombinant FSH, and recombinant LH. A urine sample must be collected immediately after ejaculation. Zygote Intrafallopian Transfer (ZIFT) Zygote Intrafallopian Transfer (ZIFT) is another variation of IVF. It can either be used to inspect and diagnose certain conditions or to surgically correct an abnormality such as removing scar tissue, endometriosis, or a damaged fallopian tube.

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Both infertility and subfertility are defined as the inability to conceive after a certain period of time (the length of which vary), so often the two terms overlap. This technique involves an injection of a single healthy sperm directly injected into mature egg. Semen is the milky fluid that a man's penis releases during orgasm. Exercise: Both too much and too little exercise can lead to fertility problems. Full history taking of both partners usually denotes the underlying problem [17-23], (Appendix 1). Eating disorders: If an eating disorder leads to serious weight loss, fertility problems may arise.

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The acrosome should be 40-70% of the size of the head, and no mid piece or tail abnormalities should be present. 37,38 The addition of 1,500 to 1,700 mg of metformin (Glucophage) daily may increase ovulation and pregnancy rates, but it does not significantly improve live birth rates over clomiphene alone. Abnormality in any of those regions may indicate abnormal sperm function and compromise the ability of sperm to fertilize the egg. About 25% of all infertility is caused by a sperm defect and 40-50% of infertility cases have a sperm defect as the main cause, or a contributing cause. The fertilized egg is then implanted in the uterus.

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In men, exposure to lead can reduce both sex drive and sperm count. Disadvantages of IVF include failure to conceive, OHSS and expensiveness. Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes. (PDF, 1 MB) Cell, 2009. In-vitro fertilization and donor insemination are major procedures involved.