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In order to perform ICSI, an egg is held via a small suction pipette, while one sperm is injected into that egg using a very fine glass needle. VITRIKAS, MD, David Grant Medical Center Family Medicine Residency, Travis Air Force Base, California Am Fam Physician. 2015 Mar 1;91(5):308-314.   Patient information: See related handout on infertility, written by the authors of this article.   Related letter: Natural Procreative Technology for Treating Infertility This clinical content conforms to AAFP criteria for continuing medical education (CME). Reversal of Vasectomy and the Treatment of Male Infertility. (PDF, 4 MB) Urologic Clinics of North America, 1981. The Male-specific Region of the Human Y Chromsome is a Mosaic of Discrete Sequence Classes. (PDF, 754 KB) Nature, 2003. Only an additional 7% of couples will conceive in the second year.

Clean, Intermittent Self-catheterization in the Treatment of Urinary Tract Disease. (PDF, 2 MB) The Journal of Urology, 1972. A Series of Monozygotic Twins Discordant for Ovarian Failure: Ovary Transplantation (Cortical versus Microvascular) and Crypreservation. (PDF, 791 KB) Human Reproduction, 2008. However, there are various scenarios where one may be advised to seek help earlier.

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Risk factors for the formation of antisperm antibodies in men include the breakdown of the blood‑testis barrier, trauma and surgery, orchitis, varicocele, infections, prostatitis, testicular cancer, failure of immunosuppression and unprotected receptive anal or oral sex with men.[23][24] Sexually transmitted infections[edit] Infections with the following sexually transmitted pathogens have a negative effect on fertility: Chlamydia trachomatis and Neisseria gonorrhoeae. Practice Committee of the American Society for Reproductive Medicine in collaboration with the Society for Reproductive Endocrinology and Infertility. (2008). Testicular Transplantation and Autotransplantation. (PDF, 8 MB) Chapter 22 of textbook, Extracorporeal and Microvascular Surgery, 1982. In closed social groups, a degree of rejection (or a sense of being rejected by the couple) may cause considerable anxiety and disappointment. A high serum estradiol level (greater than 60 to 80 pg per mL [220 to 294 pmol per L]) in conjunction with a normal FSH level has also been associated with lower pregnancy rates.

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Follicular puncture Embryo transfer Ovarian stimulation Postcoital test In-vitro cultivation 3. Round Spermatid Injection. (PDF, 422 KB) Fertility and Sterility, 2000. Search dates: January 6, 2014; January 28, 2014; February 5, 2014; and November 18, 2014. Assisted hatching: The embryologist opens a small hole in the outer membrane of the embryo, known as the zona pellucid. New Concepts in Operative Andrology: A Review. (PDF, 7 MB) International Journal of Andrology, 2000. Today, assisted reproductive techniques (ARTs) offer powerful new options.

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Similarly, there is no need for testing tubal patency for couples who will require IVF or ICSI procedure. Known uterine fibroids or endometrial polyps: Uterine abnormalities, such as fibroids that indent the endometrial cavity and endometrial polyps, can impair how the endometrium (the lining of the uterus) and embryo interact to lower implantation and pregnancy rates. But painful periods that interfere with your daily life may be a symptom of endometriosis. The ICSI process takes place following a cycle during which fertility drugs are administered to the female partner to aid in the production of multiple eggs. Other causes include Y chromosome microdeletion, a depletion of chromosome material that impedes or severely decreases spermatozoa production. Abnormal semen may not be able to carry the sperm effectively. The couple should have sex at least every two days between the 10th and 18th day after the woman starts her period. The principal indications for CC use are oligomenorrhea, especially polycystic ovarian syndrome (PCOS), and for patients with slight menstrual irregularities. Functional sperm that are present may have a normal karyotype. Between 45 and 50 percent of cases are thought to stem from factors that affect the man. The application of artificial insemination usually is made after previous medicamentous treatment. Recombination Between Palindromes P5 and P1 on the HUman Y Chromosome Causes Massive Deletions and Spermatogenic Failure. (PDF, 786 KB) The American Journal of Human Genetics, 2002.