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Microsurgery and Andrology. (PDF, 5 MB) Chapter from textbook, 1991. 37,38 The addition of 1,500 to 1,700 mg of metformin (Glucophage) daily may increase ovulation and pregnancy rates, but it does not significantly improve live birth rates over clomiphene alone.

Patients who do not ovulate because of a fault in the pituitary gland may receive this drug as an injection. Partners may become more anxious to conceive, increasing sexual dysfunction.[17] Marital discord often develops, especially when they are under pressure to make medical decisions. A rapid slide agglutination test (RSAT) kit to detect serum antibodies is commercially available. Sperm can survive as long as 5 days in the female genital tract. The pathophysiology of the disease is not well understood, but a massive extravascular accumulation of fluid occurs that is associated with a severe depletion of the intravascular volume responsible for dehydration, hemoconcentration, and electrolyte imbalance (ie, hyponatremia, hyperkalemia). [193] Ovarian hyperstimulation syndrome can be mild, moderate, or severe. [194] Mild ovarian hyperstimulation syndrome is characterized by ovarian enlargement (up to 5-12 cm in diameter), minimal ascites, and weight gain of less than 10 lb. Apparent Fertility of Human Spermatozoa from the Caput Epididymidis. (PDF, 4 MB) Journal of Andrology, 1989.

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Many uterine and tubal abnormalities detected by the HSG can be surgically corrected. In contrast, anovulation usually manifests itself as irregularity of menstrual periods, that is, unpredictable variability of intervals, duration, or bleeding. Assisted Reproductive Technology: Using Ejaculated, Fresh, and Frozen-thawed Epididymal and Testicular Spermatozoa Gives Rise to Comparable Results after Intracytoplasmic Sperm Injection. (PDF, 5 MB) Fertility and Sterility, 1995. Frequency of intercourse The couple may be advised to have sexual intercourse more often around the time of ovulation. The Disappearing Male. (PDF, 1 MB) From Towards Reproductive Certainty, 1999. Definition of Infertility Infertility is defined as the inability to conceive after 12 months of having sexual intercourse with average frequency, without the use of any form of birth control.

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However, a complete blockage of the ovaries is rarely a cause of infertility. In most cases, surgery can be performed to either reverse these blockage or to retrieve sperm directly from the epididymis and testicles. In order to accomplish this, the semen is washed with a solution safe to sperm and eggs, and then centrifuged to separate motile sperm from immotile sperm and other cells. Ovulation of the egg occurs approximately 2 weeks before the start of the next period. The Use of Epididymal Sperm in Assisted Reproduction. (PDF, 8 MB) Chapter from textbook, Frontiers in Endocrinology: Perspectives on Assisted Reproduction, 1994.

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Submucosal fibroids are the type if fibroid that has clearly been demonstrated to reduce pregnancy rate, roughly by 50%, and removal of which will double pregnancy rate. Embryo Development after ICSI Using Testicular, Epididymal and Ejaculated Spermatozoa. (PDF, 2 MB) Frontiers in Endocrinology, 1995. For this reason, a call for low-cost ART protocols have been attempt to reduce the overall current cost of IVF through limiting the rquired laboratory investigations, modifying the stimulation regimen and purchasing low-priced pre-used machines and instruments [35]. Where Dreams are Born. (PDF, 2 MB) Jewish Light, 2010. Men with Infertility Caused by AZFc Deletion can Produce Sons by Intracytoplasmic Sperm Injection, but are Likely to Transmit the Deletion and Infertility. (PDF, 102 KB) Human Reproduction, 1999. The male partner can be evaluated for infertility or subfertility using a variety of clinical interventions, and also from a laboratory evaluation of semen.” (Semen manual, 5th Edition3). This was set up on 1 August 1991 following a detailed commission of enquiry led by Mary Warnock in the 1980s A similar model to the HFEA has been adopted by the rest of the countries in the European Union. This may be because the ovaries do not contain eggs. Causes include: Surgery: Pelvic surgery can sometimes cause scarring or damage to the fallopian tubes. The presence of anti-sperm antibodies have been found in infertile men, and suppression of these antibodies with corticosteroid treatment has improved the semen quality and increased the rate of conception. 10 Data Sources: A PubMed search was completed using the key terms infertility, subfertility, treatment, etiology, and diagnosis. The opening improves the ability of the embryo to implant into the uterine lining.