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What’s on the Mind of IVF Consumers? (PDF, 627 KB) Reproductive BioMedicine Online, 2009. PDF Articles by Decade: 1970s | 1980s | 1990s | 2000s | 2010s ARTICLES FROM THE 1970s Active Lupus Glomerulitis and Hematoxylin Bodies with Normal Urinalysis. (PDF, 5 MB) The Journal of Urology, 1971. Less common factors The following other factors may also be responsible for infertility in a smaller proportion of cases: • Genetic abnormalities within eggs, sperm or both • An abnormal uterine cavity, including the presence of fibroids or polyps • Immunological infertility, whereby either the male or female partner produces anti-bodies against sperm cells or implantation of an embryo • Abnormal cervical mucus which hinders the passage of sperm to the uterus and fallopian tubes Unexplained infertility Even when investigations have been extensive, some couples will have no reason with which to explain their infertility. Congenital Adrenal Hyperplasia: Occurs when the pituitary is suppressed by increased levels of adrenal androgens.  Symptoms include low sperm count, an increased number of immature sperm cells, and low sperm cell motility.  Is treated with cortisone replacement therapy.  This condition is found in only 1 percent of infertile men. They compete with endogenous GnRH molecules for the pituitary receptors and provoke a massive release of gonadotropins into circulation.

Both infertility and subfertility are defined as the inability to conceive after a certain period of time (the length of which vary), so often the two terms overlap. If the sperm do not have the right shape, or they cannot travel rapidly and accurately towards the egg, conception may be difficult.

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This diagnosis is therefore shared by 15% of couples attempting to conceive. These questions will be regarding your medical, surgical, gynecological, and obstetric history, as well as some lifestyle questions. Long-term Economic Benefits Attributed to IVF-conceived Children: A Lifetime Tax Calculation. (PDF, 225 KB) The American Journal of Managed Care, 2008. If your cycles are infrequent or irregular, your doctor will examine you and perform the appropriate testing to discover which problem you may have and present the appropriate treatment options. There is still some controversy about their existence, but if the discoveries are true, this could mean a new treatment for infertility.[71] Stem cell therapy is really new, and everything is still under investigation.

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These adverse effects were reported in older women with advanced breast cancer who were given the drugs on a daily basis over several months. Up to 2 percent of men are thought to have suboptimal sperm. Ectopic pregnancy This is when a fertilized egg implants outside the womb, usually in a fallopian tube.

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Radiation therapy While Leydig cells are relatively radioresistant because of their low rate of cell division, the Sertoli and germ cells are extremely radiosensitive. Mumps, leading to orchitis (testicular inflammation), may cause secondary testicular atrophy in the small number of men infected after puberty. Its mechanism of action is still not well understood, but it competes for the estrogen receptor at the hypothalamus, pituitary, and ovarian levels. In this case synthetic FSH by injection or Clomid (Clomiphene citrate) via a pill can be given to stimulate follicles to mature in the ovaries. The sperm is washed in a fluid and the best specimens are selected. Sherman Silber: Be Fruitful and Multiply. (PDF, 6 MB) Lifestyles Magazine, 1999. Inhibin B levels have been reported to decrease with increasing weight, which results in decreased Sertoli cells and sperm production. Surgery for epididymal blockage: A blocked epididymis can be surgically repaired. For women aged 35, about 94% who have regular unprotected sexual intercourse get pregnant after three years of trying. Most couples (approximately 85%) will achieve pregnancy within one year of trying, with the greatest likelihood of conception occurring during the earlier months. The rising number of obese individuals may be due in part to an energy-rich diet as well as insufficient physical exercise.  In addition to other potential health risks, obesity can have a significant impact on male and female fertility. Happily, many couples treated for infertility go on to have babies. Charting of the menstrual cycle may be done by hand, or with the aid of various fertility monitors. However, for certain very poor specimens with low original concentrations of motile sperm, the use of the gradient system results in such a negligible recovery as to render it useless.