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Hormone imbalances Infertility can result from disorders of the testicles themselves or an abnormality affecting other hormonal systems including the hypothalamus, pituitary, thyroid and adrenal glands. Not being able to father a child can make a guy feel like he’s failing at one of his most primal responsibilities. Varicocele: Surgically removing a varicose vein in the scrotum may help. The results of these tests help determine the best fertility treatment. Feedback inhibition is from testosterone and inhibin. Patients who do not achieve ovulation after three to six cycles should be referred to an infertility specialist for further treatment.

This drug is administered in a pulsatile fashion every 60-120 minutes, intravenously or subcutaneously using a delivery pump. As the major causes of infertility are sperm abnormalities, ovulation dysfunction, and fallopian tube obstruction, the preliminary adviced investigations for the infertile couple should be focused on semen analysis (to be compared with the WHO reference values [27]), detection of ovarian function by hormonal assay (early follicular FSH and LH levels, and mid-luteal progesterone), and evaluation of tubal patency by hysterosalpingography (HSG) [17-32], (Appendix 3). Medications Testosterone replacement therapy, long-term anabolic steroid use, cancer medications (chemotherapy), certain antifungal medications, some ulcer drugs and certain other medications can impair sperm production and decrease male fertility. As the amount of adipose tissue increases, there is more aromatase available to convert androgens, and serum estradiol levels increase. Ovulation-inducing drugs and ovarian cancer risk: results from an extended follow-up of a large United States infertility cohort. PPT Presentation Summary : Evaluation of Fertility: A Cornerstone to Improved Reproductive Health for Women Overview.

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For a man to be fertile, the testicles must produce enough healthy sperm to be ejaculated effectively into the woman's vagina. Therefore, it is particularly important to evaluate both partners when investigating infertility. In such circumstances, it is recommended not to prescribe any medication until all basic investigations are done and its results received. Chromosomal abnormalities An estimated 6-13% of infertile men have chromosomal abnormalities (compared with 0.

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No consensus exists as to whether the medical treatment should precede surgery or vice versa. [154, 155, 156] Those who prefer medical treatment first argue that the size of the endometriosis decreases; therefore, surgery will be easier and shorter. Endometriosis may be treated through laparoscopic surgery. Malformation of the eggs themselves may complicate conception. Calcification of the Seminal Vesicles and Vas Deferens in a Uremic Patient. (PDF, 3 MB) The Journal of Urology, 1971. There are three main types of sperm antibodies: Immunoglobulin G (IgG) Immunoglobulin A (IgA) Immunoglobulin M(IgM). For example, treatment for Hodgkin disease has been estimated to lead to infertility in as many as 80-100% of patients.

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Pregnancy after Vasovasostomy for Vasectomy Reversal: A Study of Factors Followed for 10 Years. (PDF, 3 MB)Human Reproduction, 1989. Treatment of Female Infertility: Intrauterine Insemination Intrauterine insemination (IUI) is a fertility procedure in which sperm are washed (separated from the semen), concentrated, and injected directly into a woman’s uterus. The rising number of obese individuals may be due in part to an energy-rich diet as well as insufficient physical exercise.  In addition to other potential health risks, obesity can have a significant impact on male and female fertility. Treatment Treatment will depend on many factors, including the age of the person who wishes to conceive, how long the infertility has lasted, personal preferences, and their general state of health. Therefore, a total of 4 spermatids are made from each spermatocyte. High Fertilization and Pregnancy Rate after Intracytoplasmic Sperm Injection with Spermatozoa Obtained from Testicle Biopsy. (PDF, 3 MB) Human Reproduction, 1995. Some diseases: Conditions that are sometimes linked to lower fertility in males are anemia, Cushing's syndrome, diabetes, and thyroid disease. Source : Preserving your fertility - University of Kansas Hospital PPT Presentation Summary : Preserving your fertility. Surgical Management of Male Infertility. (PDF, 2 MB) Chapter 12 from textbook, Male Infertility, 1992.