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ART: Intracytoplasmic Sperm Injection (ICSI) (Continued) Once an egg is injected, it is observed for approximately 14 hours to see if fertilization has occurred (average fertilization rate is about 65%), and for 24 hours to ensure that cell division has started. Role of Epididymis in Sperm Maturation. (PDF, 3 MB) Urology, 1989. If the tubes are blocked, the sperm cannot travel into and out of the penis making it impossible for the sperm to ever meet with and fertilize an egg.

Low sperm mobility (motility): The sperm cannot "swim" as well as they should to reach the egg. 6 The initial history should cover menstrual history, timing and frequency of intercourse, previous use of contraception, previous pregnancies and outcomes, pelvic infections, medication use, occupational exposures, substance abuse, alcohol intake, tobacco use, and previous surgery on reproductive organs. Infertility and Impaired Fecundity in the United States, 1982-2010: Data from the National Survey of Family Growth.

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Hysterosalpingography: Fluid is injected into the woman's uterus and X-rays are taken to determine whether the fluid travels properly out of the uterus and into the fallopian tubes. The transit time varies with age and sexual activity but is usually from 1-12 days. The patients are classified as WHO1 (15%) - hypo-gonadotropic, hypo-estrogenic, WHO2 (80%) - normo-gonadotropic, normo-estrogenic, and WHO3 (5%) - hyper-gonadotropic, hypo-estrogenic. First, ovarian stimulation takes place; therefore, the patient initially is pre-treated with GnRH-antagonists. Women who have a body weight 10% to 15% below normal may have reduced fertility. Measures the LH in urine to detect if and when ovulation has occurred.

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Round Spermatid Injection. (PDF, 422 KB) Fertility and Sterility, 2000. Types of Infertility There are two types of infertility: primary and secondary. These abnormalities can also cause irregular bleeding between menstrual cycles. Living with male infertility When Steve S. of Joliet, Illinois was diagnosed with male infertility, he felt profound disappointment. Four alternatives are currently available to treat endometriosis: expectant therapy, surgical intervention, medical treatment, and combined therapy.

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Genital duct obstruction is a potentially curable cause of infertility and is observed in 7% of infertile patients. The Relationship of Abnormal Semen Values to Pregnancy Outcome. (PDF, 770 KB) Chapter 10 from textbook, 1992. Obese women have a higher rate of recurrent, early miscarriage compared to non-obese women. Options include intrauterine insemination (also known as IUI) or IVF with intracytoplasmic sperm injection (also known as ICSI). Expectant therapy Expectant therapy should be based on a complete workup with diagnosis of very early stages of the disease (minimal) in patients without clinical symptoms, ie, an incidental finding. [145] A second-look laparoscopy is required for follow-up observation within 6-18 months. On Regenerating the Ovary and Generating Controversy. (PDF, 37 KB) Cell, 2005. The Disappearing Y Chromosome – “I Told You So!” (PDF, 266 KB) Human Reproduction, 1997. Successful Pregnancy after Microsurgical Transplantation of an Intact Ovary. (PDF, 438 KB) The New England Journal of Medicine, 2008. There may be testicular malformations, hormone imbalance, or blockage of the man's duct system. The chromosomal pattern of the resultant embryos can be assessed with preimplantation genetic diagnosis.