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Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. Reduced fecundability in women with prenatal exposure to cigarette smoking. Previous sterilization treatment: In women who have chosen to have their fallopian tubes blocked, the process can be reversed, but the chances of becoming fertile again are not high. A complete pelvic exam should reveal any uterine hypoplasia, fibroids, adnexal tumors or cervical lesions and should indicate whether dyspareunia may be a problem.

In my case, the inability to conceive was the result of a condition called stage 4 endometriosis. A Modern Approach to Male Infertility. (PDF, 2 MB) Serono Symposia, Insights Into Infertility Newsletter, 1997. Limits were placed on language and human race as well. If necessary, they refer patients to a fertility clinic or local hospital for more specialized tests. Normal Fertilization of Human Oocytes after Testicular Sperm Extraction and Intracytoplasmic Sperm Injection.(PDF, 2 MB) Fertility and Sterility, 1994.

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However, the presence of fibroids alone doesn’t necessarily cause infertility or predispose a woman to pregnancy loss. The procedure is performed by interventional radiology and requires overnight admission for the patient. [125] It is NOT intended for patients who desire fertility. Clomiphene citrate for unexplained subfertility in women. Treatment depends on the cause of infertility and varies from ovulation-inducing drugs to surgery to ART.Continued Hysteroscopy . In this procedure, your doctor places a hysteroscope into your uterus through your cervix.

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Role of Epididymis in Sperm Maturation. (PDF, 3 MB) Urology, 1989. Symptoms can also depend on what is causing the infertility. It stimulates the ovaries to mature egg follicles.

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Low sperm mobility (motility): The sperm cannot "swim" as well as they should to reach the egg. You always have the choice to experience our sites without personalized advertising based on your web browsing activity by visiting the DAA's Consumer Choice page, the NAI's website, and/or the EU online choices page, from each of your browsers or devices. Ultrastructure of Human Sperm in Men with Congenital Absence of the Vas Deferens: Clinical Implications. (PDF, 2 MB) Fertility and Sterility, 1992. Many cases are treated with medication or may require surgical procedures. Primary Lymphoma of Kidney. (PDF, 586 KB) The Journal of Urology, 1973. Fertilization takes place outside the body, and the fertilized egg is reinserted into the woman's reproductive tract, in a procedure called embryo transfer. Worldwide, 8 to 12 percent of couples experience fertility problems. Previous sterilization treatment: In women who have chosen to have their fallopian tubes blocked, the process can be reversed, but the chances of becoming fertile again are not high. Unexplained infertility is not the same thing as having no explanation, but rather reflects the fact that the tests performed have been normal. Many more couples, however, experience involuntary childlessness for at least one year: estimates range from 12% to 28%.[4] Male infertility is responsible for 20–30% of infertility cases, while 20–35% are due to female infertility, and 25–40% are due to combined problems in both parts.[2][5] In 10–20% of cases, no cause is found.[5] The most common cause of female infertility is ovulatory problems, which generally manifest themselves by sparse or absent menstrual periods.[6] Male infertility is most commonly due to deficiencies in the semen, and semen quality is used as a surrogate measure of male fecundity.[7] Women who are fertile experience a natural period of fertility before and during ovulation, and they are naturally infertile for the rest of the menstrual cycle.


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See also
What Causes Infertility During Pregnancy
Infertility Topics for Research
The Infertility Network Uk