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Clark AM, Thornley B, Tomlinson L, Galletley C, Norman RJ. Theoretically, with this therapy, we can get artificial gamets in vitro.

2 This encompasses couples with infertility and impaired ability to get pregnant, but it does not capture those who are not married, so actual numbers may be underestimated. Cervical factors are also thought to play a minor role, although they are rarely the sole cause. A typical disease is polycystic ovarian syndrome.

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Optimal sperm conditions Although only one sperm is needed to fertilise your partner’s egg, the enzymes from multiple sperm are needed to break down the egg’s protective barrier. As the rate of getting spontaneous pregnancy among infertile or subfertile couples is lower than that among normal fertile population, it is recommended to carry out the following diagnostic, evidence-based, work-up to detect any hidden treatable cause.

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This hormone then binds to another area of the brain called the pituitary gland and leads to the release of FSH (follicle stimulating hormone), a hormone that directly binds to cells in the ovary, leading to egg growth and maturation. Sertoli cells also secrete inhibin, which provides negative feedback on the hypothalamus, and androgen-binding protein, which helps modulate androgen activity in the seminiferous tubules.

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Reduced fecundability in women with prenatal exposure to cigarette smoking. Similarly, there is no need for testing tubal patency for couples who will require IVF or ICSI procedure. If the GI symptoms persist, the medication can be administered intravaginally. Symptoms include: bloating constipation dark urine diarrhea nausea abdominal pain vomiting They are usually mild and easy to treat. Omitting unnecessary investigations, in particular couples, could reduce total cost of their infertility management without compromising their success rate. They are very common (approximately 40% of women have them them). A cumulative pregnancy rate of 80% is achieved during the first 6 cycles of therapeutic insemination. 6 The initial history should cover menstrual history, timing and frequency of intercourse, previous use of contraception, previous pregnancies and outcomes, pelvic infections, medication use, occupational exposures, substance abuse, alcohol intake, tobacco use, and previous surgery on reproductive organs. 3,4  Infertility may arise from male factors, female factors, or a combination of these (Table 15–8).