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Metformin (Glucophage): If Clomifene is not effective, metformin may help women with PCOS, especially when linked to insulin resistance. Medical treatments[edit] Medical treatment of infertility generally involves the use of fertility medication, medical device, surgery, or a combination of the following. Paternal age > or = 40 years: an important risk factor for infertility. Often, varicoceles or past infections such as mumps orchitis are the cause of sterility. For women aged 35, about 94% who have regular unprotected sexual intercourse get pregnant after three years of trying. Recovery of Spermatogenesis after Testicle Autotransplantation in an Adult Male. (PDF, 2 MB) Fertility and Sterility, 1982.

Quantitative Evaluation of Spermatogenesis by Testicular Histology in Men with Congenital Absence of the Vas Deferens Undergoing Epididymal Sperm Aspiration. (PDF, 3 MB) Human Reproduction, 1990. Reducing the risk of multiple pregnancies Injectable fertility drugs can sometimes result in multiple births, for example, twins or triplets. 41 Treatment of Unexplained Infertility Jump to section + Couples who have no identified cause of infertility should be counseled on timing of intercourse for the most fertile period (i.e., the six days preceding ovulation). Intrauterine insemination (IUI.)At the time of ovulation, sperm are injected directly up into the uterus.

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Treatment of Female Infertility: Ovulation Induction Agents The main agents used for the induction of ovulation include: Clomiphene citrate is an orally active, nonsteroidal agent structurally similar to estrogen. Infertility rates have increased by 4% since the 1980s, mostly from problems with fecundity due to an increase in age.[72] Fertility problems affect one in seven couples in the UK.

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Infertility is more likely in men who have had this condition. Men who are underweight tend to have lower sperm concentrations than those who are at a normal BMI. If conception does not occur after many months or years of trying, it can lead to stress and possibly depression. This study was carried out in accordance with the requirements of the University of Bristol Regulations and Code of Ethics for Research Programmes. Normal sperm have a smooth oval head approximately 3-5 μm long and 2-3 μm wide.

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Medications Testosterone replacement therapy, long-term anabolic steroid use, cancer medications (chemotherapy), certain antifungal medications, some ulcer drugs and certain other medications can impair sperm production and decrease male fertility. Medications, treatments, and drugs Some drugs can affect fertility in a woman. These rates, of course, readjusted down for the older women with long durations of infertility [42]. Some suggest that the number of times a couple has intercourse should be reduced to increase sperm supply, but this is unlikely to make a difference. Primary infertility is when a couple has not conceived after trying for at least 12 months without using birth control Secondary infertility is when they have previously conceived but are no longer able to. Evaluation may be initiated sooner in patients who have risk factors for infertility or if the female partner is older than 35 years. Classic Klinefelter syndrome has a 47, XXY karyotype and is caused by a nondisjunction during the first meiotic division, more commonly of maternal origin; mosaic forms are due to nondisjunction following fertilization. However, about one in five cases of infertility has no clear diagnosed cause.[73] In Britain, male factor infertility accounts for 25% of infertile couples, while 25% remain unexplained. It's used to remove polyps and fibroid tumors, divide scar tissue, and open up blocked tubes. Causes include: Surgery: Pelvic surgery can sometimes cause scarring or damage to the fallopian tubes. In patients with varicocele, there is insufficient evidence to suggest corrective surgery will increase live birth rates, despite improvement in semen analysis results. Intracytoplasmatic Sperm Injection (ICSI) An intracytoplasmatic sperm injection is also a form of artificial insemination.