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Ongoing Pregnancies and Birth after Intracytoplasmic Sperm Injection with Frozen-thawed Epididymal Spermatozoa. (PDF, 442 KB) Human Reproduction, 1995. Without an erection, it is difficult for a man to release sperm inside the vagina—and, therefore, difficult to get a woman pregnant.

Infertility is caused by primary testicular failure, and most patients are azoospermic. For women, being underweight and having extremely low amounts of body fat are associated with ovarian dysfunction and infertility and they have a higher risk for preterm birth. 47 Motivational interviewing techniques for modifiable risk factors, such as obesity, tobacco, illicit drugs, and alcohol, can decrease the targeted risk factor.

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Treatment is with exogenous gonadotropins and iron-chelating therapy. A history and physical examination can help direct the evaluation. Additional tests to determine sterility include blood tests, an ultrasound of the ovaries, hysterosalpingography to check for physical problems of the uterus and fallopian tubes. For example, treatment for Hodgkin disease has been estimated to lead to infertility in as many as 80-100% of patients. In women with anovulation, it may be an alternative after 7 - 12 attempted cycles of pituitary feedback regimens (as evidenced by clomifene citrate), since the latter ones are less expensive and more easy to control.[18] In vitro fertilization[edit] The standard procedure of in vitro fertilization includes controlled ovarian hyperstimulation with gonadotropins, but in larger doses, with the intention to induce development of supernumerary follicles.

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Being obese or overweight: This can increase the risk of infertility in women as well as men. In general, infertility is defined as the inability of couples to achieve pregnancy after ≥1 year of trying (1).

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What’s on the Mind of IVF Consumers? (PDF, 627 KB) Reproductive BioMedicine Online, 2009. Medical conditions Some medical conditions can affect fertility. 8,26,27 As opposed to laparoscopy or hysteroscopy, hysterosalpingography is a minimally invasive procedure with potentially therapeutic effects and should be considered before more invasive methods of assessing tubal patency. 10 Data Sources: A PubMed search was completed using the key terms infertility, subfertility, treatment, etiology, and diagnosis. New Concepts in Operative Andrology: A Review. (PDF, 7 MB) International Journal of Andrology, 2000. Other conditions Various other lesions and diseases, such as CNS tumors, temporal lobe seizures, and many drugs (eg, dopamine antagonists) may interrupt the hypothalamic-pituitary axis at the hypothalamus. If natural selection is the primary error correction mechanism that prevents random mutations on the Y chromosome, then fertility treatments for men with abnormal sperm (in particular ICSI) only defer the underlying problem to the next male generation. Testicular histology reveals hyalinization of seminiferous tubules.[21] Some men with Klinefelter syndrome may be able to conceive with the help of assisted reproductive techniques. This relatively simple test involves the man providing a semen sample for a lab to evaluate. The enzyme aromatase is responsible for this conversion, and is found primarily in adipose tissue. Depending on the therapeutic agent and the duration of treatment, endometriosis can be treated with oral contraceptives, progestins, androgens, or GnRH agonists. The recourse for these specimens is to remove the seminal fluid by successive media washes.