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Additionally, the sperm may be unable to cross the cervical mucus or may have ultrastructural abnormalities. Other hormones including inhibin B and leptin, may also be affected by obesity. Drugs used for both women and men[67] include clomiphene citrate, human menopausal gonadotropin (hMG), follicle-stimulating hormone (FSH), human chorionic gonadotropin (hCG), gonadotropin-releasing hormone (GnRH) analogues, aromatase inhibitors, and metformin. Cervical surgery can sometimes cause scarring or shortening of the cervix.

Treatment of tubal obstruction generally requires referral for subspecialty care. Factors contributing to the formation of antisperm antibodies in women are disturbance of normal immunoregulatory mechanisms, infection, violation of the integrity of the mucous membranes, rape and unprotected oral or anal sex. New Concepts in Operative Andrology: A Review. (PDF, 7 MB) International Journal of Andrology, 2000.

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Couples may decide to go ahead regardless if the desire to become pregnant is very strong. In some cases, the cause of infertility or subfertility could not be suspected from the history taking and clinical examination. The number of days in between each period varies each month. Dealing with Fertility Problems After Vasectomy Reversal. (PDF, 7 MB) Contemporary OB/GYN, 1978.

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38,39 Family physicians may choose to attempt ovulation induction in anovulatory women (WHO group II) with clomiphene. Polycystic ovary syndrome (PCOS): The ovaries function abnormally and ovulation may not occur. Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes. (PDF, 1 MB) Cell, 2009. Infertility is defined as the inability to become pregnant after 12 months of regular, unprotected intercourse. Partners may become more anxious to conceive, increasing sexual dysfunction.[17] Marital discord often develops, especially when they are under pressure to make medical decisions.

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Fertilized eggs are then transferred several days later into the woman’s uterus, where implantation and embryo development will hopefully occur as in a normal pregnancy. Compensatory and Obligatory Renal Growth in Rats. (PDF, 1 MB) American Journal of Physiology, 1974. In cases of poor sperm quality, intrauterine insemination can be performed. The main symptom of infertility is not getting pregnant. Refinements in the Methodology of Injection for Transvaginal Gamete Intra-Fallopian Transfer. (PDF, 2 MB) Human Reproduction, 1994. Regardless of the treatment approach, establish a 6- to 12-month interval during which a spontaneous pregnancy is expected to occur. Hysterosalpingography: Fluid is injected into the woman's uterus and X-rays are taken to determine whether the fluid travels properly out of the uterus and into the fallopian tubes. Some people find that joining a support group helps, as it offers the chance to talk to others in a similar situation. If stem cells remain viable after radiation therapy, patients may regain fertility within several years. The severity usually depends on how near to the testicles the radiation was aimed. Symptoms If a couple doesn't get pregnant after a year of unprotected intercourse, both the man and woman should be evaluated. Clean, Intermittent Self-catheterization in the Treatment of Urinary Tract Disease. (PDF, 2 MB) The Journal of Urology, 1972.