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Bhaskar Dutta/Photoshare Clinical definitions Infertility is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.”… (WHO-ICMART glossary1). “Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year. Segmental dysplasia is defined as a vas deferens with at least 2 distinct sites of vasal obstruction. Surgical therapy of a macroprolactinoma is rarely curative, although this should be considered in patients with visual-field defects or those who do not tolerate bromocriptine. A history of pelvic infections or sexually transmitted diseases: Sexually transmitted infections, such as chlamydia or gonorrhea, can cause inflammation and permanent scarring of the fallopian tubes. Idiopathic Hypercalciuria. (PDF, 1 MB) New England Journal of Medicine, 1971.

It makes the pituitary gland release more follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Symptoms depend on what is causing the infertility. Polycystic ovary syndrome (PCOS): The ovaries function abnormally and ovulation may not occur. Intracytoplasmic Sperm Injection and Infertility. (PDF, 53 KB) Nature Genetics, 2001.

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Treatment of the cause: 26. Ovulation disorders: (Hyperprolactinaemic amenorrhoea) - Women with ovulatory disorders due to hyperprolactinaemia should be offered treatment with dopamine agonists such as bromocriptine. - Consideration should be given to safety for use in pregnancy and minimising cost when prescribing. A review of records from other fertility doctors that you have seen is also important. These problems with sperm can cause male infertility. Androgen receptor dysfunction Because the androgen receptor is essential for the process of spermatogenesis, dysfunctions in this receptor can cause infertility. Infertility and impaired fecundity in the United States, 1982–2010: data from the National Survey of Family Growth. Embryo Development after ICSI Using Testicular, Epididymal and Ejaculated Spermatozoa. (PDF, 2 MB) Frontiers in Endocrinology, 1995.

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Enzymatic Digestion of Testicular Tissue May Rescue the Intracytoplasmic Sperm Injection Cycle in Some Patients with Non-obstructive Azoospermia. (PDF, 66 KB) Human Reproduction, 1998. While it may be difficult to detect infertility symptoms outright, here are some signs that may point to fertility issues: Irregular periods: The average woman’s cycle is about 28 days long.

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Sperm or egg donation: If necessary, sperm or eggs can be received from a donor. However, there are various scenarios where one may be advised to seek help earlier. ARTICLES FROM THE 2010s Ovarian Function 6 Years after Cryopreservation and Transplantation of Whole Sheep Ovaries. (PDF, 496 KB)Reproductive BioMedicine Online, 2010. Preliminary Tests of a New Reversible Male Contraceptive in Bush Dog, Speothos Venaticus: Open-ended Vasectomy and Microscopic Reversal. (PDF, 106 KB) Journal of Zoo and Wildlife, 2006. Treatment for Infertility 1) Education: We strongly believe that educating our patients about the normal process of fertility, problems that affect fertility, and treatment options will empower our patients to make the best choices. Diagnostic evaluation of the infertile female: a committee opinion. ARTICLES FROM THE 2000s Evaluation and Treatment of Male Infertility. (PDF, 17 MB) Clinical Obstetrics and Gynecology, 2000.