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Semm published over 1000 papers in various journals.[4] He also produced over 30 endoscopic films and more than 20,000 colored slides to teach and inform interested colleagues about his technique. As the major causes of infertility are sperm abnormalities, ovulation dysfunction, and fallopian tube obstruction, the preliminary adviced investigations for the infertile couple should be focused on semen analysis (to be compared with the WHO reference values [27]), detection of ovarian function by hormonal assay (early follicular FSH and LH levels, and mid-luteal progesterone), and evaluation of tubal patency by hysterosalpingography (HSG) [17-32], (Appendix 3). 389 KB ARTICLES FROM THE 1980s Microsurgical Reversal of Female Sterilization: The Role of Tubal Length. (PDF, 2 MB) Fertility and Sterility, 1980. National Collaborating Centre for Women's and Children's Health. Paternal age > or = 40 years: an important risk factor for infertility.

Further investigations may be requested according to the clinical presentation and the results of preliminary tests. A paper published in JAVMA (Journal of the American Veterinary Medical Association) in 2005 showed that dogs spayed laparoscopically experienced significantly less pain (65%) than those that were spayed with traditional "open" methods.[8] Arthroscopy, thoracoscopy, cystoscopy are all performed in veterinary medicine today. Sperm are then collected, washed, and added to the eggs in the dish. Semm established several standard procedures that were regularly performed, such as ovarian cyst enucleation, myomectomy, treatment of ectopic pregnancy and finally laparoscopic-assisted vaginal hysterectomy (nowadays termed as cervical intra-fascial Semm hysterectomy).

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Male infertility tests: Going under the microscope Identifying the cause of a man's infertility is as much an art as a science. “The first step is an evaluation by a physician specializing in male infertility,” says Stephen Shaban, MD, a urologist specializing in male reproductive medicine and microsurgery in Raleigh, North Carolina. In vitro fertilization[edit] IVF is the most commonly used ART.

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The Relationship of Abnormal Semen Values to Pregnancy Outcome. (PDF, 770 KB) Chapter 10 from textbook, 1992. Lifestyle and environmental factors such as smoking, alcohol and drugs, poor eating habits, exposure to increases in testicular temperature (for example, in professions where the worker spends many hours sitting down) and exposure to toxins are factors that compromise semen quality. Eating disorders such as anorexia nervosa are also associated with extremely low BMI. It is said to be the most reliable way of confirming whether ovulation has occurred.[12] Women may also use ovulation predictor kits (OPKs) which detect the increase in luteinizing hormone (LH) levels that usually indicates imminent ovulation. WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Couple.

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Epididymal and Testicular Spermatozoa and Intracytoplasmic Sperm Injection. (PDF, 7 MB) Assisted Reproduction Reviews, 1996. Overheated testicles: Causes include an undescended testicle, a varicocele, or varicose vein in the scrotum, the use of saunas or hot tubs, wearing tight clothes, and working in hot environments. These may be purchased over the counter and allow couples to predict the most fertile days in the cycle. When the magic moment arrives, about 150 million sperm are ejaculated in a half-teaspoon of semen through the penis. Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. Classic Klinefelter syndrome has a 47, XXY karyotype and is caused by a nondisjunction during the first meiotic division, more commonly of maternal origin; mosaic forms are due to nondisjunction following fertilization. Tests and trials are available, but testing does not always reveal a specific cause. Careful monitoring during treatment and pregnancy can help reduce the risk of complications. Through this technique, your physician can diagnose abnormalities such as fibroids or polyps within the uterine cavity, and via narrow instruments that run through the hysterosope, can remove or correct the great majority of these abnormalities. One of the requirements for this procedure is that a woman should have at least 1 undamaged fallopian tube. Seventy-five percent of patients have testicular atrophy and primary testicular failure due to degeneration of the seminiferous tubules.