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Bensdorp AJ, Cohlen BJ, Heineman MJ, Vandekerckhove P. Unexplained infertility[edit] In the US, up to 20% of infertile couples have unexplained infertility.[61] In these cases abnormalities are likely to be present but not detected by current methods. The Fate of Non-absorbable Intraureteral Suture. (PDF, 233 KB) The Journal of Urology, 1973. 8,46 Obesity impairs fertility and the response to fertility treatments, including in vitro fertilization; therefore, it is advisable to counsel patients who are obese to lose weight before conception or infertility treatments. Partners may become more anxious to conceive, increasing sexual dysfunction.[17] Marital discord often develops, especially when they are under pressure to make medical decisions.

Klinefelter�s Syndrome: Is a genetic condition in which each cell in the human body has an additional X chromosome--men with Klinefelter�s Syndrome have one Y and two X chromosomes.  Physical symptoms include peanut-sized testicles and enlarged breasts.  A chromosome analysis is used to confirm this analysis.  If this condition is treated in its early stages (with the drug hCG), sperm production may commence and/or improve.  However, Klinefelter�s Syndrome eventually causes all active testicular structures to atrophy.  Once testicular failure has occurred, improving fertility is impossible. IVF/ICSI is a process by which the oocyte is fertilized by a sperm outside the body: in vitro, and then a gamete retransferred intrauterine. Some methods may be used in concert with other methods. Existing definitions of infertility lack uniformity, rendering comparisons in prevalence between countries or over time problematic. Prior surgeries Certain surgeries may prevent you from having sperm in your ejaculate, including vasectomy, inguinal hernia repairs, scrotal or testicular surgeries, prostate surgeries, and large abdominal surgeries performed for testicular and rectal cancers, among others. If the egg does not travel, it can be harder to conceive naturally.

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Thus women whose pregnancy spontaneously miscarries, or whose pregnancy results in a still born child, without ever having had a live birth would present with primarily infertility. (Trends in prevalence4). Those who prefer surgery first argue that because the size of endometriosis decreases, lesions that cannot be observed during surgery may be present; therefore, the operation is less than ideal and is associated with an increased chance for early recurrence. This can be done by a urine test, basal body temperature chart, progesterone test and/or endometrial biopsy. These problems with sperm can cause male infertility. Religious leaders' opinions on fertility treatments; for example, the Roman Catholic Church views infertility as a calling to adopt or to use natural treatments (medication, surgery, or cycle charting) and members must reject assisted reproductive technologies. Patients with adrenal hyperplasia and other disorders must be treated with prednisone.

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Some respond by actively avoiding the issue altogether; middle-class men are the most likely to respond in this way.[21] In the United States some treatments for infertility, including diagnostic tests, surgery and therapy for depression, can qualify one for Family and Medical Leave Act leave. Premature Ejaculation: Is defined as an inability to control the ejaculatory response for at least thirty seconds following penetration.  Premature ejaculation becomes a fertility problem when ejaculation occurs before a man is able to fully insert his penis into his partner�s vagina.  Premature ejaculation can be overcome by artificial insemination or by using a behavioral modification technique called the �squeeze technique� which desensitizes the penis.

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Histologically, Leydig cells are polygonal with eosinophilic cytoplasm. For a woman to conceive, certain things have to happen: vaginal intercourse must take place around the time when an egg is released from her ovary; the system that produces eggs has to be working at optimum levels; and her hormones must be balanced.[54] For women, problems with fertilisation arise mainly from either structural problems in the Fallopian tube or uterus or problems releasing eggs. It delivers a constant supply of Gn-RH to the pituitary gland, which alters the production of hormone, allowing the doctor to induce follicle growth with FSH. Excess alcohol consumption: This may lower male fertility. The woman may be given a low dose of ovary stimulating hormones. Ovulation should be documented by serum progesterone level measurement at cycle day 21. Constant irrigation with Ringer lactate solution and heparin prevents fibrin formation. An ultrasound scan can detect an ectopic pregnancy. The new generations of available gonadotropins are produced by genetically engineered mammalian cells (ie, Chinese hamster ovary cells), in which the gene coding for the alpha and beta FSH subunits has been inserted (follitropin alfa [eg, Gonal F] and follitropin beta [eg, Follistim AQ]). [185] Recombinant LH may beaddedtorecombinantFSHprotocolsasanalternative,particularlyuseful in patients with hypothalamic amenorrhea. Retrograde Ejaculation: Is a condition in which semen is ejaculated into the bladder rather than out through the urethra because the bladder sphincter does not close during ejaculation.  If this disorder is present, ejaculate volume is small and urine may be cloudy after ejaculation.  This condition affects 1. Hysteroscopy is the inspection of the uterine cavity through the cervix by a hysteroscope attached to a camera which projects to a screen. Algorithm for infertility evaluation. (ART = assisted reproductive technology.) Infertility Evaluation Figure 1.


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