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Role of Epididymis in Sperm Maturation. (PDF, 3 MB) Urology, 1989. European Association of Urology guidelines on male infertility: the 2012 update. Sperm Retrieval for Azoospermia and Intracytoplasmic Sperm Injection Success Rates – A Personal Overview.(PDF, 1 MB) Human Fertility, 2010.

However, about one in five cases of infertility has no clear diagnosed cause.[73] In Britain, male factor infertility accounts for 25% of infertile couples, while 25% remain unexplained. 50% are female causes with 25% being due to anovulation and 25% tubal problems/other.[74] In Sweden, approximately 10% of couples wanting children are infertile.[75] In approximately one third of these cases the man is the factor, in one third the woman is the factor, and in the remaining third the infertility is a product of factors on both parts. Generally, evaluation should be offered to couples who have not conceived after one year of unprotected vaginal intercourse. A sperm count of under 15 million is considered low. If he has two X chromosomes and one Y chromosome, as in Klinefelter's syndrome, the testicles will develop abnormally and there will be low testosterone and a low sperm count or no sperm.

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Lifestyle and environmental factors such as smoking, alcohol and drugs, poor eating habits, exposure to increases in testicular temperature (for example, in professions where the worker spends many hours sitting down) and exposure to toxins are factors that compromise semen quality. 7 million women reported impaired ability to get pregnant or carry a baby to term. In theory, it is possible to conceive on any of these 6 days that occur before and during ovulation. Medications Testosterone replacement therapy, long-term anabolic steroid use, cancer medications (chemotherapy), certain antifungal medications, some ulcer drugs and certain other medications can impair sperm production and decrease male fertility. S. women, or 6% of the married population 15 to 44 years of age, reported infertility, and 6.

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Medical treatments[edit] Medical treatment of infertility generally involves the use of fertility medication, medical device, surgery, or a combination of the following. Ovulation problems can be a result of:  polycystic ovary syndrome (PCOS) thyroid problems – both an overactive thyroid gland and an underactive thyroid gland can prevent ovulation premature ovarian failure – where a woman's ovaries stop working before the age of 40 Scarring from surgery Pelvic surgery can damage and scar the fallopian tubes, which link the ovaries to the womb. 5 mg PO qd and increased to 5 mg once tolerance is built. Successful Pregnancy and Delivery after Calcium Ionophore Oocyte Activation in a Normozoospermic Patient with Previous Failed Fertilization after Intracytoplasmic Sperm Injection. (PDF, 57 KB) Fertility and Sterility, 2003. The woman may be given a low dose of ovary stimulating hormones.

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Diverse Spermatogenic Defects in Humans Caused by Y Chromosome Deletions Encompassing a Novel RNA-binding Protein Gene. (PDF, 2 MB) Human Reproduction, 1996. In many cases, cornual obstruction diagnosed on HSG represents simple cornual spasm. Microscopic Vasectomy Reversal. (PDF, 31 MB) Fertility and Sterility, 1977. Clinical diagnostic testing for the cytogenetic and molecular causes of male infertility: the Mayo Clinic experience. Radiation therapy: If this is aimed near the reproductive organs, it can increase the risk of fertility problems. Radiation therapy: This can impair sperm production. 3 Learn more about how age can impact your fertility, and why it’s best to seek advice to conceive as early as possible. Treatment of Secondary Amenorrhea and Oligo-ovulation Once the diagnosis is established and any other endocrinopathy has been excluded, the ovulation induction agent of choice depends on a functioning hypothalamic-pituitary-ovarian axis. Exogenous testosterone should never be administered in an attempt to boost sperm production because it actually decreases intratesticular testosterone levels owing to feedback inhibition of GnRH release. He also developed a medical instrument company Wisap in Munich, Germany, which still produces various endoscopic instruments of high quality. At least one open tube is required for IUI, and any sperm abnormality cannot be severe, otherwise the sperm will not be able to swim to and fertilize the egg. Causes in men The following are common causes of infertility in men. Your physician will refer you to a reproductive urologist if appropriate. A Physical Map of the Human Y Chromosome. (PDF, 160 KB) Nature, 2001. 17 Evaluation of male infertility starts with a history and physical examination focusing on previous fertility, pelvic or inguinal surgeries, systemic diseases, and exposures. 32. Semen used is filtered for washing and grading through one of various processes use.