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Histologic endometrial dating is not considered reliable nor is it predictive of fertility. Age: Male fertility starts to fall after 40 years. A Modern Approach to Male Infertility. (PDF, 2 MB) Serono Symposia, Insights Into Infertility Newsletter, 1997. Risk factors for the formation of antisperm antibodies in men include the breakdown of the blood‑testis barrier, trauma and surgery, orchitis, varicocele, infections, prostatitis, testicular cancer, failure of immunosuppression and unprotected receptive anal or oral sex with men.[23][24] Sexually transmitted infections[edit] Infections with the following sexually transmitted pathogens have a negative effect on fertility: Chlamydia trachomatis and Neisseria gonorrhoeae. Most couples (approximately 85%) will achieve pregnancy within one year of trying, with the greatest likelihood of conception occurring during the earlier months. Many infertile couples have had some previous assessment for their infertility and this data should be cautiously reviewed.

Ovulation induction in polycystic ovary syndrome [published corrections appear in J Obstet Gynaecol Can. About 25% of all infertility is caused by a sperm defect and 40-50% of infertility cases have a sperm defect as the main cause, or a contributing cause. Once the fluid containing the eggs is removed from the follicles into the vials, they are handed to the embryologist who finds the eggs, places them in tiny droplets on a Petri dish, and then fertilizes the eggs using their partner’s or donor sperm. Infertility is defined as the inability to become pregnant after 12 months of regular, unprotected intercourse.

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Although many of these can be treated through surgery or hormonal substitutions, some may be indefinite.[59] Infertility associated with viable, but immotile sperm may be caused by primary ciliary dyskinesia. Gonadotropins can trigger ovulation when Clomid or Serophene don't work. Y Chromosome Deletions in Azoospermic and Severely Oligozoospermic Men Undergoing Intracytoplasmic Sperm Injection after Testicular Sperm Extraction. (PDF, 336 KB) Human Reproduction, 1998. Pregnancy Caused by Sperm from Vasa Efferentia. (PDF, 1 MB) Fertility and Sterility, 1988. Mumps, leading to orchitis (testicular inflammation), may cause secondary testicular atrophy in the small number of men infected after puberty.

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Some large breeds of dogs may not have their first estrus until they are ≥2 yr old, and some individuals and some breeds typically have only one estrous cycle each year. The results of these tests help determine the best fertility treatment. Conventional IVF vs ICSI (Intra Cytoplasmic Sperm Injection) for Patients Requiring Microsurgical Epididymal Sperm Aspiration (MESA). (PDF, 4 MB) Chapter from textbook, Frontiers in Endocrinology: Perspectives on Assisted Reproduction, 1994.

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5) Endometrial polyps: Endometrial polyps are finger-like growths in the uterine cavity arising from the lining of the uterus, called the endometrium, These abnormalities are rarely associated with cancer (<1% in a woman before menopause), but polyps are can decrease fertility by up to 50% according to some studies. The surgeon can remove implants and scar tissue, and this may reduce pain and aid fertility. Hormonal analysis Around 3% of cases of male infertility are estimated to be due primarily to a hormonal cause. Microsurgical Reversal of Tubal Sterilization: Factors Affecting Pregnancy Rate, with Long-term Follow-up. (PDF, 2 MB) Obstetrics & Gynecology, 1984. Only an additional 7% of couples will conceive in the second year.