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A history and physical examination can help direct the evaluation. Screening tests include increased plasma 17-hydroxylase and urine 17-ketosteroids. They may benefit from referral to a physician comfortable with prescribing pulsatile administration of gonadotropin-releasing hormone or gonadotropins with luteinizing hormone activity to induce ovulation. It's used to remove polyps and fibroid tumors, divide scar tissue, and open up blocked tubes. In women whose ovulation is suppressed by hyperprolactinemia (high blood levels of the pituitary hormone prolactin), ovulation may be induced with prolactin-suppressing drugs.

This leads to the final maturation and release of the egg. Chemotherapy: Some chemotherapy drugs can result in ovarian failure. About 25% of all infertility is caused by a sperm defect and 40-50% of infertility cases have a sperm defect as the main cause, or a contributing cause. Fresh Ovarian Tissue and Whole Ovary Transplantation. (PDF, 373 KB) Seminars in Reproductive Medicine, 2009.

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The physician or WHNP may also suggest using a conception cap cervical cap, which the patient uses at home by placing the sperm inside the cap and putting the conception device on the cervix, or intrauterine insemination (IUI), in which the doctor or WHNP introduces sperm into the uterus during ovulation, via a catheter. The fertilized embryo is then transferred to womb. Men should undergo evaluation with a semen analysis.

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The more fetuses there are, the higher the risk of premature labor. Large submucosal uterine fibroids may make the uterus' cavity bigger, increasing the distance the sperm has to travel.

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6) Male factors affecting sperm function: Male factor infertility has been associated as a contributing factor causing infertility in 40-50% percent of cases, and as the sole cause for infertility in 15-20% percent of cases. Checking the woman’s fallopian tubes to make sure they are not blocked. In my case, the inability to conceive was the result of a condition called stage 4 endometriosis. Blood test: This can assess hormone levels and whether a woman is ovulating. Blood tests Depending on the individual couple's situation, various blood tests on either the female or the male may be needed. Epidemiological definition of infertility (for monitoring and surveillance) Women of reproductive age (15–49 years) at risk of becoming pregnant (not pregnant, sexually active, not using contraception and not lactating) who report trying unsuccessfully for a pregnancy for two years or more. (Reproductive Health Indicators) Infertility as a disability Disability: Infertility generates disability (an impairment of function), and thus access to health care falls under the Convention on the Rights of Persons with Disability. If an endocrinopathy, such as hyperprolactinemia, is diagnosed, the underlying cause should be treated. Preliminary Tests of a New Reversible Male Contraceptive in Bush Dog, Speothos Venaticus: Open-ended Vasectomy and Microscopic Reversal. (PDF, 106 KB) Journal of Zoo and Wildlife, 2006. Extra Renal Function in Patients with Duplication Anomaly: Obligatory and Compensatory Renal Growth. (PDF, 1 MB) The Journal of Urology, 1974. Vasectomy and its Microsurgical Reversal. (PDF, 17 MB) Urologic Clinics of North America, 1978.