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A defect in any of these sperm structures may result in infertility that will not be detected by semen analysis.[60] Antisperm antibodies cause immune infertility.[23][24] Cystic fibrosis can lead to infertility in men. Blood test: This can assess hormone levels and whether a woman is ovulating. M. genitalium infection is associated with increased risk of infertility.[25][26] Genetic[edit] A Robertsonian translocation in either partner may cause recurrent spontaneous abortions or complete infertility.[citation needed] Mutations to NR5A1 gene encoding Steroidogenic Factor-1 (SF-1) have been found in a small subset of men with non-obstructive male factor infertility where the cause is unknown.

Clinical examination Full clinical examination of both partners usually stands for the underlying physical problem [17-22,24-26], (Appendix 2). 29 When the semen analysis is abnormal, referral to a male fertility specialist or reproductive endocrinologist is warranted. Round Spermatid Injection. (PDF, 422 KB) Fertility and Sterility, 2000. Biopsy reveals maturation arrest or germ cell aplasia.

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Infertility Counselling Winnipeg

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Congenital blockage of the ductal system An increased rate of duct obstruction is observed in children of mothers who were exposed to DES during pregnancy. The chance of a live birth following treatment is nearly 50% [25]. The Disappearing Male. (PDF, 1 MB) From Towards Reproductive Certainty, 1999. Mumps, leading to orchitis (testicular inflammation), may cause secondary testicular atrophy in the small number of men infected after puberty.

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Ovarian hyperstimulation syndrome The ovaries can swell, leak excess fluid into the body, and produce too many follicles, the small fluid sacs in which an egg develops. Intrauterine insemination (IUI): At the time of ovulation, a fine catheter is inserted through the cervix into the uterus to place a sperm sample directly into the uterus. Risk factors for male infertility include obesity, age (over 40 -- yes, men also have biological clocks), current or previous infection of an STD, smoking, or excessive drinking. The enzyme aromatase is responsible for this conversion, and is found primarily in adipose tissue. Possible problems could be that the egg is not released at the optimum time for fertilization, that it may not enter the fallopian tube, sperm may not be able to reach the egg, fertilization may fail to occur, transport of the zygote may be disturbed, or implantation fails.

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549 KB Effect of Age on Male Fertility. (PDF, 5 MB) Chapter from textbook, Seminars in Reproductive Endocrinology, 1991. 40. ď‚—Luteal phase support: - Should be offer luteal phase support with progesterone till 8 weeks of gestation. - Different form of progesterone with different routes of administration are available, RCT are taking place comparing efficacy of different forms. ď‚—Generally, success rates lie between 40% and 60% per cycle. Patients who do not achieve ovulation after three to six cycles should be referred to an infertility specialist for further treatment. It is specially oriented for cancer patients, whose sperm is destroyed due to the gonadotoxic treatment they are submitted to.[70] Ovaric stem cells: it is thought that women have a finite number of follicles from the very beginning. It may also prevent the sperm from reaching the egg. In other cases, the cause is suspected to be immunological or genetic; it may be that each partner is independently fertile but the couple cannot conceive together without assistance. Ovulation usually occurs within the 32-40 hours after the indicative color change. Endometriosis can only be confirmed by surgery, usually laparoscopy. And as aging occurs, egg quality, or the likelihood of an egg being genetically normal, decreases as well. Testicular histology typically reveals a decreased number of Leydig cells and decreased spermatogenesis. Algorithm for infertility evaluation. (ART = assisted reproductive technology.) Infertility Evaluation Figure 1. Submucosal fibroids are the type if fibroid that has clearly been demonstrated to reduce pregnancy rate, roughly by 50%, and removal of which will double pregnancy rate. In humans, infertility is the inability to become pregnant after one year of intercourse without contraception involving a male and female partner.[2] There are many causes of infertility, including some that medical intervention can treat.[3] Estimates from 1997 suggest that worldwide about five percent of all heterosexual couples have an unresolved problem with infertility. The optimum fertile period is around 23 years of age when only 5% of women have issues getting pregnant.


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See also
Local Infertility Support Group
Nova Infertility Center Kolkata
Infertility Treatment in Polycystic Ovaries