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Steroids used to build muscles can shrink the testes and may lead to decreased sperm production. Apparently there are only 0,014% of them (this could be an explanation of why they were not discovered until now).

Medications in use for this effect are mainly clomifene citrate and tamoxifen (both being selective estrogen-receptor modulators), as well as letrozole (an aromatase inhibitor.[17] Follicle-stimulating hormone (FSH), directly stimulating the ovaries. IUI with the partner’s sperm can be used as a potentially effective treatment for infertility in women under age of 45 except for cases with tubal blockage, very poor egg quality, ovarian failure and severe male factor infertility (very low sperm count or very poor sperm shape or mobility). Refinements in the Methodology of Injection for Transvaginal Gamete Intra-Fallopian Transfer. (PDF, 2 MB) Human Reproduction, 1994. Some physical effects may also result from treatment.

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Donor semen should be free from any STI-producing organisms, including HIV. Obese women have a higher rate of recurrent, early miscarriage compared to non-obese women. It's used to remove polyps and fibroid tumors, divide scar tissue, and open up blocked tubes. Those motile and viable sperm are then placed in a very small amount of solution, and then very gently and painlessly injected into the uterine cavity using a very thin, soft, and flexible catheter.

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Severe ovarian hyperstimulation syndrome is characterized by easily palpable ovaries, severe ascites, nausea, vomiting, diarrhea, shortness of breath, hydrothorax, peripheral edema, oliguria, hemoconcentration (eg, hematocrit level >48% and hemoglobin level >16 g), and creatinine level greater than 1. 8) Unexplained/other: Sometimes a full evaluation does not reveal the cause of infertility.

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Tests and trials are available, but testing does not always reveal a specific cause. Transplantation of a Human Testis for Anorchia. (PDF, 19 MB) Fertility and Sterility, 1978. Other factors that can affect a woman's chances of conceiving include being overweight or underweight,[56] or her age as female fertility declines after the age of 30.[57] Sometimes it can be a combination of factors, and sometimes a clear cause is never established. They can interfere with implantation or block the fallopian tube, preventing sperm from fertilizing the egg. Lack of estrogen brings about decreased spinnbarkeit of the cervical mucus. In closed social groups, a degree of rejection (or a sense of being rejected by the couple) may cause considerable anxiety and disappointment. A Physical Map of the Human Y Chromosome. (PDF, 160 KB) Nature, 2001. Exposure to some chemicals: Some pesticides, herbicides, metals, such as lead, and solvents have been linked to fertility problems in both men and women.